Register

Sections:

2900-001: Fall 2014 – September 29, 2014 – February 21, 2015
2900-002: Winter 2015 – January 12 – May 23, 2015
2900-003: Spring 2014 – April 13 2015 – July 25, 2015

DOWNLOAD LECTURE SCHEDULE

NOTE: Students registered in this course must access the online lectures via The UofT Portal. This requires a UTORID. Your UTORID will be provided for you by e-mail a week before the course starts. Kindly register in time to start the course on the first day.

Assigned Lecture Number

Topic

Instructor

1A

Introduction to SCS2900

Profs. Arnot and Laposa

1B Introduction to Pharmacology

2

What is a drug?

Prof. Ross

Interview I: Importance of New Drug Development, Prof. Ross Prof. Arnot

3

Drugs as molecules

Prof. Ross

4

Overview of Pharmacokinetics and Physiology Concepts

Prof. Burnham

5

Route of Administration

Prof. Burnham

Clinical Vignette #1

Formulations

Dr. Shear

6

Mechanism of Drug Absorption

Prof. Burnham

7

Drug Distribution I

Prof. Burnham

8

Drug Distribution II

Prof. Burnham

9

Introduction to Clearance and Biotransformation

Prof. Burnham

Clinical Vignette #2

Anaesthetics

Dr. Shear

10

Biotransformation I

Prof. Burnham

11

Biotransformation II

Prof. Burnham

 

Visit #1: Tyndale Laboratory

 

12

Total Body Clearance

Prof. Burnham

13

Organ Clearance

Prof. Burnham

14

Clinical Pharmacokinetics

Prof. Burnham

Clinical Vignette #3

What is Clinical Pharmacology?

Dr Shear

15

Introduction to Pharmacodynamics

Prof. Ross

16

Drug–Receptor Interactions

Prof. Ross

 

Visit #2: Ramsey/Salahpour Laboratory

17

Drug Classification I – Agonist

Prof. Ross

18

Drug Classification II – Antagonists and Partial Agonists

Prof. Ross

19

Receptor Diversity & Enzymes as Targets

Prof. Ross

20

Enzyme Targets II: ASA & NSAIDS

Prof. Ross

21

Enzyme Targets III: ACE-Inhibitiors and ACHase Inhibitors

Prof. Ross

22

Enzyme Targets IV: Antibiotics

Prof. Ross

Clinical Vignette #4 HIV – AIDS Drug Therapy Dr. Shear

23

GPCR I: Introduction

Dr George

24

GPCR II: Drugs that Modulate

Dr George

25

GPCR III: Quirks and Quarks of Receptor Signaling

Dr. George

Clinical Vignette #5 Clinical Agents that Target GPCRs Dr. George
26 Drugs that Target: GC & PDE Prof. Ross

27

Tyrosine Kinase Receptors I

Prof. Ross

28

Tyrosine Kinase Receptors II: Pharmacology

Prof. Ross

29

Drug Transporters as Drug Targets

Prof. Grant

Interview II: Importance of Drug Transporters, Dr. Piquette-Miller

30

Membrane Physiology and Ion Channels

Prof. Grant

31

VGIC I: Structure and Function

Prof. Grant

32

VGIC II: Modulation

Prof. Grant

33

LGIC I: Nicotinic Ach Receptors

Prof. Grant

34

LGIC II: GABA-A and Glutamate Receptors

Prof. Grant

Clinical Vignette #6

Muscle Relaxants

Dr Shear

35

Nuclear Receptors I

Prof. Grant

36

Nuclear Receptors II: Steroid Hormone

Prof. Grant

37

Nuclear Receptors III: Non-Steroids

Prof. Grant

Clinical Vignette #7

Environmental Factors and Genes Dr. Shear

38

Genes as Targets

Prof. Grant

39

Immunopharmacology

Prof. Grant

40

Drug Variability

Prof. Grant

41

Pharmacogenetics

Prof. Grant
Interview III: Application of PGx, Dr. Tyndale

42

Drug-Drug Interactions

Prof. Grant

43

Adverse Drug Reactions

Prof. Grant

Clinical Vignette #8

Geriatric Pharmacology

Dr Shear

44

Introduction to Toxicology

Prof. Grant

45

Teratogenesis

Prof. Grant

46

Perinatal Pharmacology

Prof. Grant

Visit #3: Motherisk at Sick Childrens Hospital, Dr. Gideon Koren

 

47

Drug Misuse

Prof. Ross

 

Interview #3 – History of Drug Misuse, Dr Harold Kalant

Prof. Ross

48

Natural and Herbal Compounds in Performance and Therapeutics

Prof. Ross

49

Drugs in Sports

Prof. Ross

50

Review

Prof. Ross

51

Wrap Up

Profs. Arnot & Laposa

EXAM: Organized by School of Graduate Studies